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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARFGAP3
All Species:
23.94
Human Site:
Y378
Identified Species:
58.52
UniProt:
Q9NP61
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP61
NP_001135765.1
516
56928
Y378
W
D
D
S
S
D
S
Y
W
K
K
E
T
S
K
Chimpanzee
Pan troglodytes
XP_001171224
516
56901
Y378
W
D
D
S
S
D
S
Y
W
K
K
E
T
S
K
Rhesus Macaque
Macaca mulatta
XP_001107803
516
56806
Y378
W
D
D
S
S
D
S
Y
W
K
K
E
T
S
K
Dog
Lupus familis
XP_848847
517
57143
Y379
W
D
D
S
S
E
S
Y
W
K
K
E
T
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8S3
523
57437
Y385
W
D
D
G
A
D
S
Y
W
K
K
D
S
S
R
Rat
Rattus norvegicus
Q4KLN7
525
57652
Y387
W
D
D
S
A
D
S
Y
W
K
K
D
S
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512573
489
53316
E353
S
D
S
F
W
N
K
E
S
A
R
D
T
D
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001032507
536
58567
E397
S
F
S
S
W
A
L
E
K
E
E
P
K
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09531
529
57893
S390
K
E
D
D
F
F
D
S
F
E
T
Q
P
V
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O82171
395
43079
A260
P
Q
V
V
S
H
V
A
P
P
K
S
S
G
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
96.7
88.7
N.A.
80.5
80.3
N.A.
62
N.A.
N.A.
56.5
N.A.
N.A.
N.A.
35.1
N.A.
Protein Similarity:
100
96.3
98.2
94.1
N.A.
88.9
87.8
N.A.
73.8
N.A.
N.A.
71
N.A.
N.A.
N.A.
54.6
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
66.6
73.3
N.A.
13.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
100
N.A.
33.3
N.A.
N.A.
20
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
32.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
20
10
0
10
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
70
70
10
0
50
10
0
0
0
0
30
0
20
0
% D
% Glu:
0
10
0
0
0
10
0
20
0
20
10
40
0
0
0
% E
% Phe:
0
10
0
10
10
10
0
0
10
0
0
0
0
0
10
% F
% Gly:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
10
0
0
0
0
0
10
0
10
60
70
0
10
0
40
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
10
10
0
10
10
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
20
% R
% Ser:
20
0
20
60
50
0
60
10
10
0
0
10
30
50
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
0
50
0
0
% T
% Val:
0
0
10
10
0
0
10
0
0
0
0
0
0
10
0
% V
% Trp:
60
0
0
0
20
0
0
0
60
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _